Article
A complex crosstalk between polymorphic microRNA target sites and AD prognosis.
RNA biology - 1 Jan 2000
Mallick Bibekanand, Ghosh Zhumur
Abstract excerpt
Genetic variation associated with different diseases interferes with microRNA-mediated regulation by creating, destroying, or modifying microRNA (miRNA) binding sites. Alzheimer's disease (AD) is a common neurodegenerative disorder that affects cognitive function in the elderly and has associated genetic variation within the diseased genome. We investigated the extent to which these SNPs interfere with miRNA gene...
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