Article
Differential modulation of the cellular and humoral immune responses in Drosophila is mediated by the endosomal ARF1-Asrij axis.
Scientific reports - 8 Mar 2017
Khadilkar Rohan J, Ray Arindam, Chetan D R, Sinha Arghyashree RoyChowdhury, Magadi Srivathsa S, Kulkarni Vani, Inamdar Maneesha S
Abstract excerpt
How multicellular organisms maintain immune homeostasis across various organs and cell types is an outstanding question in immune biology and cell signaling. In Drosophila, blood cells (hemocytes) respond to local and systemic cues to mount an immune response. While endosomal regulation of Drosophila hematopoiesis is reported, the role of endosomal proteins in cellular and humoral immunity is not well-studied....
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