Article
ARF1-GTP regulates Asrij to provide endocytic control of Drosophila blood cell homeostasis.
Proceedings of the National Academy of Sciences of the United States of America - 1 Apr 2014
Khadilkar Rohan J, Rodrigues Diana, Mote Ridim Dadasaheb, Sinha Arghyashree Roychowdhury, Kulkarni Vani, Magadi Srivathsa Subramanya, Inamdar Maneesha S
Abstract excerpt
Drosophila melanogaster larval hematopoiesis is a well-established model to study mechanisms that regulate hematopoietic niche maintenance and control of blood cell precursor (prohemocyte) differentiation. Molecules that perturb niche function affect the balance between prohemocytes and differentiated hemocytes. The conserved hemocyte-specific endosomal protein Asrij is essential for niche function and...
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