Article
Forecasting Fat Fibrosis.
Cell metabolism - 7 Mar 2017
Shook Brett, Rodeheffer Matthew S
Abstract excerpt
Excess ECM and fibrosis of white adipose tissue (WAT) is associated with tissue dysfunction and type 2 diabetes. In this issue of Cell Metabolism, Marcelin et al. (2017) elucidate a key mechanism behind WAT fibrosis in which the activation of PDGFRα on adipocyte precursors drives this population toward a fibrotic phenotype.
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