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Article

In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding.

Cell metabolism - 4 Apr 2012

Lee Yun-Hee, Petkova Anelia P, Mottillo Emilio P, Granneman James G

Abstract excerpt

Nutritional and pharmacological stimuli can dramatically alter the cellular phenotypes in white adipose tissue (WAT). Utilizing genetic lineage tracing techniques, we demonstrate that brown adipocytes (BA) that are induced by β3-adrenergic receptor activation in abdominal WAT arise from the proliferation and differentiation of cells expressing platelet-derived growth factor receptor alpha (PDGFRα), CD34, and...

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Share to Adipocytes
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Share to Adipose Tissue, White

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptor, Platelet-Derived Growth Factor alpha

Share to Receptors, Adrenergic, beta-3

Source

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Identifiers

PMID: 22482730
DOI: 10.1016/j.cmet.2012.03.009
PMCID: PMC3322390

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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