Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic control of adipose tissue development and adult tissue homeostasis by platelet-derived growth factor receptor alpha

19 Jun 2020

Abstract excerpt

Adipocytes arise from distinct progenitor populations during developmental and adult stages but little is known about how developmental progenitors differ from adult progenitors. Here, we investigate the role of platelet-derived growth factor receptor alpha (PDGFRα) in the divergent regulation of the two different adipose progenitor cells (APCs). Using in vivo adipose lineage tracking and deletion mouse models,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Adipose Tissue and Metabolism
Share to Mesenchymal stem cell research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32553115
DOI: 10.7554/elife.56189

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic control of adipose tissue development and adult tissue homeostasis by platelet-derived growth factor receptor alphaPMID 32553115Read ↗

PDGFRα/PDGFRβ signaling balance modulates progenitor cell differentiation into white and beige adipocytesSemantic proximity Read ↗

In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding.Semantic proximity Read ↗

Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult miceSemantic proximity Read ↗

Single-cell transcriptomic analysis reveals dynamic activation of cellular signaling pathways regulating beige adipogenesisSemantic proximity Read ↗

Independent Stem Cell Lineages Regulate Adipose Organogenesis and Adipose HomeostasisSemantic proximity Read ↗

Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of AdipogenesisSemantic proximity Read ↗

Characterization of Cre recombinase activity for in vivo targeting of adipocyte precursor cells.Semantic proximity Read ↗

Parallel Lineage-Tracing Studies Establish Fibroblasts as the Prevailing In Vivo Adipocyte ProgenitorSemantic proximity Read ↗

Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansionSemantic proximity Read ↗

Obesity modifies cell fate plasticity of Pdgfrα-expressing adipocyte progenitors to promote an aberrant mammary microenvironmentSemantic proximity Read ↗

Identification and characterization of PDGFRα+ mesenchymal progenitors in human skeletal muscleSemantic proximity Read ↗

Obesity modifies cell fate plasticity of <i>Pdgfrα-</i> expressing adipocyte progenitors to promote an aberrant mammary microenvironmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.