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The Adipocyte Acquires a Fibroblast-Like Transcriptional Signature in Response to a High Fat Diet

11 Feb 2020

Abstract excerpt

Visceral white adipose tissue (vWAT) expands and undergoes extensive remodeling during diet-induced obesity. Much is known about the contribution of various stromal vascular cells to the remodeling process, but less is known of the changes that occur within the adipocyte as it becomes progressively dysfunctional. Here, we performed a transcriptome analysis of isolated vWAT adipocytes to assess global pathway...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 32047213
DOI: 10.1038/s41598-020-59284-w

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