Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The role of driver and subclonal mutations in pathogenesis of primary myelofibrosis].

Magyar onkologia - 8 Mar 2017

Mózes Réka, Gángó Ambrus, Boha Zsófia, Csomor Judit, Bödör Csaba

Abstract excerpt

Primary myelofibrosis (PMF) is a Philadelphia chromosome negative, clonal myeloproliferative neoplasm characterised by a progressive nature. Morphologically, the bone marrow biopsy shows features of abnormal proliferation of terminally differentiated megakaryocytes and subsequent bone marrow fibrosis. The molecular landscape of PMF includes phenotypic driver mutations (JAK2 V617F, CALR and MPL) which represent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow
Share to ASXL1 gene
Share to CALR gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MPL gene

Share to SRSF2 gene

Share to Mutation

Share to Primary Myelofibrosis

Share to Prognosis

Source

Identifiers

PMID: 28273187

Genes

ASXL1
CALR
IDH1
JAK2
MPL
TET2
SRSF2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The role of driver and subclonal mutations in pathogenesis of primary myelofibrosis].PMID 28273187Read ↗

Molecular Pathogenesis and Clinical Significance of Driver Mutations in Primary Myelofibrosis: A Review.Semantic proximity Read ↗

The Genetic Basis of Primary Myelofibrosis and Its Clinical Relevance.Semantic proximity Read ↗

[Research progress on molecular pathogenesis of myeloproliferative neoplasms].Semantic proximity Read ↗

Clonal Hematopoiesis and Mutations of Myeloproliferative NeoplasmsSemantic proximity Read ↗

The Role and Impact of Non-driver Gene Mutations in Myelofibrosis.Semantic proximity Read ↗

Molecular pathogenesis of the myeloproliferative neoplasms.Semantic proximity Read ↗

Pathogenesis and management of high molecular risk myeloproliferative neoplasmsSemantic proximity Read ↗

Integration of Mutations and Karyotype Towards a Genetics-Based Prognostic Scoring System (GPSS) for Primary MyelofibrosisSemantic proximity Read ↗

Detection of driver and subclonal mutations in myelofibrosis: clinical impact on pharmacologic and transplant based treatment strategies.Semantic proximity Read ↗

Triple-Negative Primary Myelofibrosis: a Bone Marrow Pathology Group (BMPG) studySemantic proximity Read ↗

Myeloproliferative neoplasms: Current molecular biology and genetics.Semantic proximity Read ↗

Myelofibrosis: Genetic Characteristics and the Emerging Therapeutic Landscape.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.