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Article

[Research progress on molecular pathogenesis of myeloproliferative neoplasms].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2011

Liu Liu, Xiao Zhi-Jian

Abstract excerpt

Classical BCR/ABL fusion gene negative myeloproliferative neoplasms (MPN), including polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF), are clonal hematopoietic malignancies sharing in common origin in a multipotential hematopoietic stem cell. The phenotypic variability of the three entities can not be elucidated by JAK2V617F mutation only. Recent discoveries indicated that...

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Source

Identifiers

PMID: 21362261

Genes

ASXL1
BCR
TET2

Provenance

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