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Article

Myeloproliferative neoplasms: Current molecular biology and genetics.

Critical reviews in oncology/hematology - 1 Feb 2016

Saeidi Kolsoum

Abstract excerpt

Myeloproliferative neoplasms (MPNs) are clonal disorders characterized by increased production of mature blood cells. Philadelphia chromosome-negative MPNs (Ph-MPNs) consist of polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). A number of stem cell derived mutations have been identified in the past 10 years. These findings showed that JAK2V617F, as a diagnostic marker...

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Topics

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Share to DNA Methyltransferase 3A
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polycythemia Vera

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Share to Proto-Oncogene Proteins c-cbl

Share to Receptors, Thrombopoietin

Share to Thrombocythemia, Essential

Source

Identifiers

PMID: 26697989
DOI: 10.1016/j.critrevonc.2015.11.004

Genes

CALR
JAK2
ASXL1
CBL
HMGA2
IDH1
IDH2
IKZF1
RUNX1
TET2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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