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Article

Further investigation of phenotypes and confounding factors of progressive ratio performance and feeding behavior in the BACHD rat model of Huntington disease.

PloS one - 1 Jan 2017

Clemensson Erik Karl Håkan, Clemensson Laura Emily, Fabry Benedikt, Flunkert Stefanie, Riess Olaf, Wronski Robert, Nguyen Huu Phuc

Abstract excerpt

Huntington disease is an inherited neurodegenerative disorder characterized by motor, cognitive, psychiatric and metabolic symptoms. We recently published a study describing that the BACHD rat model of HD shows an obesity phenotype, which might affect their motivation to perform food-based behavioral tests. Further, we argued that using a food restriction protocol based on matching BACHD and wild type rats' food...

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Identifiers

PMID: 28273120
DOI: 10.1371/journal.pone.0173232
PMCID: PMC5342229

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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