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Article

Weight loss in Huntington disease increases with higher CAG repeat number

3 Nov 2008

Abstract excerpt

OBJECTIVE: Huntington disease (HD) is a hereditary neurodegenerative disorder caused by an expanded number of CAG repeats in the huntingtin gene. A hallmark of HD is unintended weight loss, the cause of which is unknown. In order to elucidate the underlying mechanisms of weight loss in HD, we studied its relation to other disease characteristics including motor, cognitive, and behavioral disturbances and CAG...

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PMID: 18981372
DOI: 10.1212/01.wnl.0000334276.09729.0e

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