Article
Identification of receptor contact site involved in receptor-G protein coupling.
Nature - 1 Jan 2000
Sullivan K A, Miller R T, Masters S B, Beiderman B, Heideman W, Bourne H R
Abstract excerpt
The mammalian G proteins transduce information from extracellular signals, including neurotransmitters, hormones and sensory stimuli, into regulation of effector enzymes or ion channels within cells. Triggered by appropriate extracellular signals, receptor proteins specifically activate members o...
Topics
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Cell Line
- GTP-Binding Proteins
- Mutation
- Protein Conformation
- Receptors, Cell Surface
- Structure-Activity Relationship