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Article

Identification of receptor contact site involved in receptor-G protein coupling.

Nature - 1 Jan 2000

Sullivan K A, Miller R T, Masters S B, Beiderman B, Heideman W, Bourne H R

Abstract excerpt

The mammalian G proteins transduce information from extracellular signals, including neurotransmitters, hormones and sensory stimuli, into regulation of effector enzymes or ion channels within cells. Triggered by appropriate extracellular signals, receptor proteins specifically activate members of the G protein family by catalysing replacement of GDP by GTP at the guanine nucleotide binding site. Like the...

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PMID: 2827032
DOI: 10.1038/330758a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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