Relation of Obstructive Sleep Apnea and a Common Variant at Chromosome 4q25 to Atrial Fibrillation.

doi:10.1016/j.amjcard.2017.01.038

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Article

Relation of Obstructive Sleep Apnea and a Common Variant at Chromosome 4q25 to Atrial Fibrillation.

The American journal of cardiology - 1 May 2017

Patel Neel J, Wells Quinn S, Huang Shi, Upender Raghu P, Darbar Dawood, Monahan Ken

Abstract excerpt

Obstructive sleep apnea (OSA) and single nucleotide polymorphisms (SNPs) at the 4q25 locus are associated with increased risk of atrial fibrillation (AF). Whether these associations are independent of traditional risk factors for AF remains unknown. Using billing code queries and manual chart review, we assembled a cohort of adults that underwent overnight polysomnography and at least 1 12-lead electrocardiogram....

Topics

Aged
Aged, 80 and over
Atrial Fibrillation
Case-Control Studies
Chromosomes, Human, Pair 4
Electrocardiography
Female
Genetic Predisposition to Disease
Genotype
Humans
Logistic Models

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Odds Ratio

Polymorphism, Single Nucleotide

Polysomnography

Risk Factors

Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 28258728
DOI: 10.1016/j.amjcard.2017.01.038
PMCID: PMC5392162

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-28258728-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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