Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.

doi:10.1161/CIRCGENETICS.109.849075

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Article

Variation in the 4q25 chromosomal locus predicts atrial fibrillation after coronary artery bypass graft surgery.

Circulation. Cardiovascular genetics - 1 Oct 2009

Body Simon C, Collard Charles D, Shernan Stanton K, Fox Amanda A, Liu Kuang-Yu, Ritchie Marylyn D, Perry Tjörvi E, Muehlschlegel Jochen D, Aranki Sary, Donahue Brian S, Pretorius Mias, Estrada Juan-Carlos, Ellinor Patrick T, Newton-Cheh Christopher, Seidman Christine E, Seidman J G, Herman Daniel S, Lichtner Peter, Meitinger Thomas, Pfeufer Arne, Kääb Stefan, Brown Nancy J, Roden Dan M, Darbar Dawood

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF) is the most common adverse event following coronary artery bypass graft surgery. A recent study identified chromosome 4q25 variants associated with AF in ambulatory populations. However, their role in postoperative AF is unknown. We hypothesized that genetic variants in the 4q25 chromosomal region are independently associated with postoperative AF after coronary artery bypass...

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PMID: 20031626
DOI: 10.1161/CIRCGENETICS.109.849075
PMCID: PMC2801871

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