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Article

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

Annals of diagnostic pathology - 1 Feb 2017

Herpel Esther, Rieker Ralf J, Dienemann Hendrik, Muley Thomas, Meister Michael, Hartmann Arndt, Warth Arne, Agaimy Abbas

Abstract excerpt

The chromatin remodeling switch sucrose nonfermentable (SWI/SNF) complex has been increasingly implicated in the pathogenesis and dedifferentiation of neoplasms from several organs with prognostic and potential therapeutic implications. We herein investigated the expression of the SWI/SNF complex catalytic subunits SMARCA4 (BRG1) and SMARCA2 (BRM) in 316 consecutive non-small cell lung cancer (NSCLC) specimens on...

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Source

Identifiers

PMID: 28038711
DOI: 10.1016/j.anndiagpath.2016.10.006

Genes

SMARCA4
SMARCA2
TTF1
SMARCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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