Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus.

Molecular endocrinology (Baltimore, Md.) - 1 Nov 2008

Jin Tianru, Liu Ling

Abstract excerpt

Since the relationship between TCF7L2 (also known as TCF-4) polymorphisms and type 2 diabetes mellitus was identified in 2006, extensive genome-wide association examinations in different ethnic groups have further confirmed this relationship. As a component of the bipartite transcription factor beta-catenin/TCF, TCF7L2 is important in conveying Wnt signaling during embryonic development and in regulating gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes Mellitus, Type 2
Share to Insulin-Secreting Cells
Share to Models, Biological

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Risk Factors

Share to Signal Transduction

Share to TCF Transcription Factors

Share to Transcription Factor 7-Like 2 Protein

Share to Wnt Proteins

Source

Identifiers

PMID: 18599616
DOI: 10.1210/me.2008-0135

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus.PMID 18599616Read ↗

The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspectiveSemantic proximity Read ↗

TCF7L2 genetic defect and type 2 diabetes.Semantic proximity Read ↗

The role of transcription factor 7‐like 2 in metabolic disordersSemantic proximity Read ↗

The broad pathogenetic role of TCF7L2 in human diseases beyond type 2 diabetes.Semantic proximity Read ↗

Current Understanding on Role of the Wnt Signaling Pathway Effector TCF7L2 in Glucose HomeostasisSemantic proximity Read ↗

[Association between polymorphisms of TCF7L2 and type 2 diabetes with special reference to incretin action].Semantic proximity Read ↗

The Role of TCF7L2 in Type 2 Diabetes.Semantic proximity Read ↗

TCF7L2 and type 2 diabetes--we WNT to know.Semantic proximity Read ↗

TCF7L2 and Glucose Metabolism: Time to Look Beyond the PancreasSemantic proximity Read ↗

Wnt signaling in pancreatic islets.Semantic proximity Read ↗

Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes in a Finnish sample.Semantic proximity Read ↗

Type 2 diabetes susceptibility gene TCF7L2 and its role in beta-cell function.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.