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Article

Admixture mapping and subsequent fine-mapping suggests a biologically relevant and novel association on chromosome 11 for type 2 diabetes in African Americans.

PloS one - 1 Jan 2014

Jeff Janina M, Armstrong Loren L, Ritchie Marylyn D, Denny Joshua C, Kho Abel N, Basford Melissa A, Wolf Wendy A, Pacheco Jennifer A, Li Rongling, Chisholm Rex L, Roden Dan M, Hayes M Geoffrey, Crawford Dana C

Abstract excerpt

Type 2 diabetes (T2D) is a complex metabolic disease that disproportionately affects African Americans. Genome-wide association studies (GWAS) have identified several loci that contribute to T2D in European Americans, but few studies have been performed in admixed populations. We first performed a GWAS of 1,563 African Americans from the Vanderbilt Genome-Electronic Records Project and Northwestern University...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Chromosomes, Human, Pair 11

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Source

Open in PubMed Open full text

Identifiers

PMID: 24595071
DOI: 10.1371/journal.pone.0086931
PMCID: PMC3940426

Genes

TCIRG1
CHKA

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