Article
ATRX status correlates with 11 C-methionine uptake in WHO grade II and III gliomas with IDH1 mutations.
Brain tumor pathology - 1 Jan 2017
Ogishima Takahiro, Tamura Kaoru, Kobayashi Daisuke, Inaji Motoki, Hayashi Shihori, Tamura Reina, Nariai Tadashi, Ishii Kenji, Maehara Taketoshi
Abstract excerpt
Recent studies on gliomas have shown frequent alterations in the alpha-thalassemia/mental retardation syndrome X-linked gene (ATRX). This study was designed to determine whether ATRX status correlates with uptake of 11C-methionine in WHO grades II and III gliomas. Sixty-two patients underwent 11C-methionine positron emission tomography scans prior to histological diagnosis. The tumor-to-normal ratio (T/N) of...
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