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Article

A nomogram strategy for identifying the subclassification of IDH mutation and ATRX expression loss in lower-grade gliomas.

European radiology - 1 May 2022

Wu Shiman, Zhang Xi, Rui Wenting, Sheng Yaru, Yu Yang, Zhang Yong, Yao Zhenwei, Qiu Tianming, Ren Yan

Abstract excerpt

OBJECTIVES: To construct a radiomics nomogram based on multiparametric MRI data for predicting isocitrate dehydrogenase 1 mutation (IDH +) and loss of nuclear alpha thalassemia/mental retardation syndrome X-linked expression (ATRX -) in patients with lower-grade gliomas (LrGG; World Health Organization [WHO] 2016 grades II and III). METHODS: A total of 111 LrGG patients (76 mutated IDH and 35 wild-type IDH) were...

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PMID: 35133485
DOI: 10.1007/s00330-021-08444-1

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