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Article

Incidence of biomarkers in high-grade gliomas and their impact on survival in a diverse SouthEast Asian cohort - a population-based study.

BMC cancer - 31 Jan 2020

Ang Samantha Ya Lyn, Lee Lester, See Angela An Qi, Ang Ting Yao, Ang Beng Ti, King Nicolas Kon Kam

Abstract excerpt

BACKGROUND: Gliomas consist of a heterogeneous group of tumors. This study aimed to report the incidences of O6-methylguanine-DNA-methyltransferase (MGMT) promoter methylation, 1p19q co-deletion, isocitrate dehydrogenase (IDH) gene mutations, and inactivating mutations of alpha-thalassemia/mental retardation syndrome X-linked (ATRX) in high-grade gliomas in an ethnically diverse population. METHODS: Records of...

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Activities of Daily Living
Asia, Southeastern
Chromosomes, Human, Pair 1
DNA Modification Methylases
DNA Repair Enzymes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Isocitrate Dehydrogenase

Neoplasm Grading

X-linked Nuclear Protein

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Identifiers

PMID: 32005184
DOI: 10.1186/s12885-020-6536-x
PMCID: PMC6993394

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