Article
Steady state peripheral blood provides cells with functional and metabolic characteristics of real hematopoietic stem cells.
Journal of cellular physiology - 1 Jan 2018
Bourdieu Antonin, Avalon Maryse, Lapostolle Véronique, Ismail Sadek, Mombled Margaux, Debeissat Christelle, Guérinet Marianne, Duchez Pascale, Chevaleyre Jean, Vlaski-Lafarge Marija, Villacreces Arnaud, Praloran Vincent, Ivanovic Zoran, Brunet de la Grange Philippe
Abstract excerpt
Hematopoietic stem cells (HSCs), which are located in the bone marrow, also circulate in cord and peripheral blood. Despite high availability, HSCs from steady state peripheral blood (SSPB) are little known and not used for research or cell therapy. We thus aimed to characterize and select HSCs from SSPB by a direct approach with a view to delineating their main functional and metabolic properties and the...
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