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Article

Genetic and environmental influences on mean diffusivity and volume in subcortical brain regions.

Human brain mapping - 1 May 2017

Gillespie Nathan A, Neale Michael C, Hagler Donald J, Eyler Lisa T, Fennema-Notestine Christine, Franz Carol E, Lyons Michael J, McEvoy Linda K, Dale Anders M, Panizzon Matthew S, Kremen William S

Abstract excerpt

Increased mean diffusivity (MD) is hypothesized to reflect tissue degeneration and may provide subtle indicators of neuropathology as well as age-related brain changes in the absence of volumetric differences. Our aim was to determine the degree to which genetic and environmental variation in subcortical MD is distinct from variation in subcortical volume. Data were derived from a sample of 387 male twins (83 MZ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28240386
DOI: 10.1002/hbm.23544
PMCID: PMC5810123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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