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Article

Evidence for genetic variance in white matter hyperintensity volume in normal elderly male twins.

Stroke - 1 Jun 1998

Carmelli D, DeCarli C, Swan G E, Jack L M, Reed T, Wolf P A, Miller B L

Abstract excerpt

BACKGROUND AND PURPOSE: White matter hyperintensities (WMHs), as detected by MRI, are common among the elderly and are frequently interpreted as representing a subclinical form of ischemic brain damage. We used volumetric MR techniques to investigate the contribution of genes and the environment to measures of brain morphology in a sample of community dwelling elderly male twins. METHODS: Brain MR (1.5 T) scans...

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PMID: 9626291
DOI: 10.1161/01.str.29.6.1177

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