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Article

Untangling the role of one-carbon metabolism in colorectal cancer risk: a comprehensive Bayesian network analysis.

Scientific reports - 24 Feb 2017

Myte Robin, Gylling Björn, Häggström Jenny, Schneede Jörn, Magne Ueland Per, Hallmans Göran, Johansson Ingegerd, Palmqvist Richard, Van Guelpen Bethany

Abstract excerpt

The role of one-carbon metabolism (1CM), particularly folate, in colorectal cancer (CRC) development has been extensively studied, but with inconclusive results. Given the complexity of 1CM, the conventional approach, investigating components individually, may be insufficient. We used a machine learning-based Bayesian network approach to study, simultaneously, 14 circulating one-carbon metabolites, 17 related...

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Identifiers

PMID: 28233834
DOI: 10.1038/srep43434
PMCID: PMC5324061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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