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Article

Genetically predicted 486 blood metabolites in relation to risk of colorectal cancer: A Mendelian randomization study.

Cancer medicine - 1 Jun 2023

Yun Zhangjun, Guo Ziwei, Li Xiao, Shen Yang, Nan Mengdie, Dong Qing, Hou Li

Abstract excerpt

BACKGROUND: Metabolic disorders are a hallmark feature of cancer. However, the evidence for the causality of circulating metabolites to promote or prevent colorectal cancer (CRC) is still lacking. We performed a two-sample Mendelian randomization (MR) analysis to assess the causality from genetically proxied 486 blood metabolites to CRC. METHODS: Genome-wide association study (GWAS) data for exposures were...

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PMID: 37132247
DOI: 10.1002/cam4.6022
PMCID: PMC10315807

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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