Article
A genome-wide association study identifies a novel candidate locus at the DLGAP1 gene with susceptibility to resistant hypertension in the Japanese population.
Scientific reports - 30 Sept 2021
Takahashi Yasuo, Yamazaki Keiko, Kamatani Yoichiro, Kubo Michiaki, Matsuda Koichi, Asai Satoshi
Abstract excerpt
Numerous genetic variants associated with hypertension and blood pressure are known, but there is a paucity of evidence from genetic studies of resistant hypertension, especially in Asian populations. To identify novel genetic loci associated with resistant hypertension in the Japanese population, we conducted a genome-wide association study with 2705 resistant hypertension cases and 21,296 mild hypertension...
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