Article
[Correlations between genetic variations of glutathione synthetase gene and the response to platinum-based chemotherapy and prognosis of small cell lung cancer patients].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 23 Feb 2017
Feng T, Li H M, Yuan P, Yu D K, Ma F, Tan W W, Du Z L, Yang J, Huang Y, Lin D X, Xu B H, Tan W
Abstract excerpt
Objective: To explore the associations between genetic variations of glutathione synthetase gene (GSS) and response to platinum-based chemotherapy of small cell lung cancer(SCLC), and to analyze the influencing factors on survival. Methods: Four haplotype-tagging single nucleotide polymorphisms (htSNPs) of GSS were genotyped by Sequenom MassARRAY methods in 903 SCLC patients who received platinum-based...
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