Article
[Genetic variation in DNA repair gene RAD52 is associated with the response to platinum-based chemotherapy in SCLC patients].
Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Jul 2016
Li H M, Yuan P, Yu D K, Ma F, Tan W W, Feng T, Yang J, Huang Y, Lin D X, Xu B H, Tan W
Abstract excerpt
OBJECTIVE: To explore the associations between genetic variations of DNA repair gene RAD52 and response to platinum-based chemotherapy of small cell lung cancer (SCLC), and to analyze the influencing factors on survival. METHODS: Nine haplotype-tagging single nucleotide polymorphisms (htSNPs) of RAD52 were genotyped by Sequenom Mass ARRAY technology in 939 SCLC patients who received platinum-based chemotherapy,...
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