Article
[Correlation of genetic polymorphisms in nucleotide excision repair system to sensitivity of advanced non-small cell lung cancer patients to platinum-based chemotherapy].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Dec 2005
Yuan Peng, Miao Xiao-Ping, Zhang Xue-Mei, Wang Zhong-Hua, Tan Wen, Zhang Xiang-Ru, Sun Yan, Xu Bing-He, Lin Dong-Xin
Abstract excerpt
BACKGROUND & OBJECTIVE: DNA repair system plays an important role in tumor sensitivity to platinum-based chemotherapy. This study was to examine the correlations of polymorphisms in nucleotide excision repair system to sensitivity of advanced non-small cell lung cancer (NSCLC) to platinum-based chemotherapy. METHODS: Treatment outcomes of 200 advanced NSCLC patients, treated with platinum-based chemotherapy, were...
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