Article
Sarcoidosis extent relates to molecular variability.
Clinical and experimental immunology - 1 Jun 2017
Monast C S, Li K, Judson M A, Baughman R P, Wadman E, Watt R, Silkoff P E, Barnathan E S, Brodmerkel C
Abstract excerpt
The molecular basis of sarcoidosis phenotype heterogeneity and its relationship to effective treatment of sarcoidosis have not been elucidated. Peripheral samples from sarcoidosis subjects who participated in a Phase II study of golimumab [anti-tumour necrosis factor (TNF)-α] and ustekinumab [anti-interleukin (IL)-12p40] were used to measure the whole blood transcriptome and levels of serum proteins. Differential...
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