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Article

Sarcoidosis Blood Transcriptome Reflects Lung Inflammation and Overlaps with Tuberculosis

19 Aug 2011

Abstract excerpt

RATIONALE: Sarcoidosis is a granulomatous disease of unknown etiology, although M. tuberculosis may play a role in the pathogenesis. The traditional view holds that inflammation in sarcoidosis is compartmentalized to involved organs. OBJECTIVES: To determine whether whole blood gene expression signatures reflect inflammatory pathways in the lung in sarcoidosis and whether these signatures overlap with...

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PMID: 21852540
DOI: 10.1164/rccm.201106-1143oc

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