Advances in understanding the immunopathology of sarcoidosis and implications on therapy.

Abstract excerpt

INTRODUCTION: Sarcoidosis is a multi-systemic granulomatous disease of unknown aetiology. Ethnicity and environmental factors may influence disease incidence, phenotype and severity. AREAS COVERED: Predisposing genes are mainly involved in T cell and macrophage function, antigen presentation and recognition, and extra-cellular matrix turnover. No definitive relationship has been established with any proposed...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Chronic Disease
• Share to Granuloma
• Share to Immunosuppression Therapy