Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprint

16 Feb 2017

Abstract excerpt

We present here a quantitative molecular blueprint of the three major glycerophospholipid (GPL) classes, phosphatidylcholine (PC), phosphatidylserine (PS), and phosphatidylethanolamine (PE), in retina and six regions of the brain in C57Bl6 mice at 2, 10, and 26 months of age. We found an age-related increase in molecular species containing saturated and monoenoic FAs and an overall decrease in the longer-chain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Liver Disease Diagnosis and Treatment
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28202633
DOI: 10.1194/jlr.m070714

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprintPMID 28202633Read ↗

Quantitative determination of longitudinal CNS cholesterol loss during myelin damage and repairSemantic proximity Read ↗

The aging mouse lipidomeSemantic proximity Read ↗

Cholesterol Metabolism in Aging and Age-Related DisordersSemantic proximity Read ↗

Fatty acid metabolism changes in association with neurobehavioral deficits in animal models of fetal alcohol spectrum disordersSemantic proximity Read ↗

Quantitative Imaging and Characterization of Ganglioside Diversity in Mouse and Human Brain TissuesSemantic proximity Read ↗

A lipidome landscape of aging in miceSemantic proximity Read ↗

Spatial MALDI-MSI Reveals a Coordinated Vicious Cycle of Oxidative Membrane Damage and Ceramide-Driven Sphingolipid Dysregulation in the Chronically Neuroinflamed BrainSemantic proximity Read ↗

Brain DHA increases in APOE3, but not in APOE4 mice, despite robust brain EPA increase during LPC n-3 supplementation in both genotypes.Semantic proximity Read ↗

The effects of APOE4 and familial Alzheimer's disease mutations on free fatty acid profiles in mouse brain are age- and sex-dependent.Semantic proximity Read ↗

PLCγ2 deficiency compromises systemic immune tolerance and erodes myelin homeostasis while enhancing oxidative metabolism in the mouse brainSemantic proximity Read ↗

Integrative lipidomics of brain and plasma uncovers sex-specific metabolic signatures in Parkinson’s diseaseSemantic proximity Read ↗

Lysophosphatidylinositol-acyltransferase-1 (LPIAT1) is required to maintain physiological levels of PtdIns and PtdInsP(2) in the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.