AGER gene polymorphisms and soluble receptor for advanced glycation end product in patients with idiopathic pulmonary fibrosis.

doi:10.1111/resp.12995

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Article

AGER gene polymorphisms and soluble receptor for advanced glycation end product in patients with idiopathic pulmonary fibrosis.

Respirology (Carlton, Vic.) - 1 Jul 2017

Yamaguchi Kakuhiro, Iwamoto Hiroshi, Horimasu Yasushi, Ohshimo Shinichiro, Fujitaka Kazunori, Hamada Hironobu, Mazur Witold, Kohno Nobuoki, Hattori Noboru

Abstract excerpt

BACKGROUND AND OBJECTIVE: The receptor for advanced glycation end product (RAGE) is a multiligand cell-surface receptor abundantly expressed in the lung. RAGE/ligand interaction has been postulated to participate in the pathogenesis of inflammatory diseases, while soluble RAGE (sRAGE) might act as a decoy receptor. A functional polymorphism rs2070600 in the gene coding RAGE (AGER) might modulate its receptor...

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PMID: 28198072
DOI: 10.1111/resp.12995

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AGER

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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