Article
Plasma Soluble Receptor for Advanced Glycation End Products in Idiopathic Pulmonary Fibrosis.
Annals of the American Thoracic Society - 1 May 2017
Manichaikul Ani, Sun Li, Borczuk Alain C, Onengut-Gumuscu Suna, Farber Emily A, Mathai Susan K, Zhang Weiming, Raghu Ganesh, Kaufman Joel D, Hinckley-Stukovsky Karen D, Kawut Steven M, Jelic Sanja, Liu Wen, Fingerlin Tasha E, Schwartz David A, Sell Jessica L, Rich Stephen S, Barr R Graham, Lederer David J
Abstract excerpt
RATIONALE: The receptor for advanced glycation end products (RAGE) is underexpressed in idiopathic pulmonary fibrosis (IPF) lung, but the role of RAGE in human lung fibrosis remains uncertain. OBJECTIVES: To examine (1) the association between IPF risk and variation at rs2070600, a functional missense variant in AGER (the gene that codes for RAGE), and (2) the associations between plasma-soluble RAGE (sRAGE)...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.