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Article

A high frequency of PALB2 mutations in Jamaican patients with breast cancer.

Breast cancer research and treatment - 1 Apr 2017

Lerner-Ellis Jordan, Donenberg Talia, Ahmed Humayun, George Sophia, Wharfe Gilian, Chin Sheray, Lowe Dwight, Royer Robert, Zhang Shiyu, Narod Steven, Hurley Judith, Akbari Mohammad R

Abstract excerpt

PURPOSE: Jamaica is an island nation with one of the highest breast cancer incidence rates in the Caribbean (40/100,000 per year). The contribution of cancer susceptibility gene mutations to the burden of breast cancer in Jamaica has not yet been explored. We sought to determine the prevalence of germline mutations in BRCA1, BRCA2, and PALB2 in 179 unselected Jamaican women with breast cancer. METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28194609
DOI: 10.1007/s10549-017-4148-1

Genes

PALB2
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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