Article
Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes.
PloS one - 1 Jan 2017
Eve Alexander M J, Place Elsie S, Smith James C
Abstract excerpt
Tmem88a is a transmembrane protein that is thought to be a negative regulator of the Wnt signalling pathway. Several groups have used antisense morpholino oligonucleotides in an effort to characterise the role of tmem88a in zebrafish cardiovascular development, but they have not obtained consistent results. Here, we generate an 8 bp deletion in the coding region of the tmem88a locus using TALENs, and we have gone...
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