Article
Using the Zebrafish as an Approach to Examine the Mechanisms of Vertebrate Erythropoiesis.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2018
Kafina Martin D, Paw Barry H
Abstract excerpt
The zebrafish, Danio rerio, is a powerful model for the study of erythropoiesis and defining the genetic basis of hematological diseases. The mechanisms of erythroid differentiation are highly conserved in the zebrafish, permitting translational research studies and the modeling of erythropoiesis in higher vertebrates. An advantage of the system is the ability to manipulate gene expression and observe the effect...
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