Article
Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jul 2005
Qian Feng, Zhen Fenghua, Ong Chinthing, Jin Suk-Won, Meng Soo Hui, Stainier Didier Y R, Lin Shuo, Peng Jinrong, Wen Zilong
Abstract excerpt
Zebrafish is an excellent model organism for studying vertebrate development and human disease. With the availability of increased numbers of zebrafish mutants and microarray chips, gene expression profiling has become a powerful tool for identification of downstream target genes perturbed by a specific mutation. One of the obstacles often encountered, however, is to isolate large numbers of zebrafish mutant...
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