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Article

Novel cardiovascular gene functions revealed via systematic phenotype prediction in zebrafish.

Development (Cambridge, England) - 1 Jan 2014

Musso Gabriel, Tasan Murat, Mosimann Christian, Beaver John E, Plovie Eva, Carr Logan A, Chua Hon Nian, Dunham Julie, Zuberi Khalid, Rodriguez Harold, Morris Quaid, Zon Leonard, Roth Frederick P, MacRae Calum A

Abstract excerpt

Comprehensive functional annotation of vertebrate genomes is fundamental to biological discovery. Reverse genetic screening has been highly useful for determination of gene function, but is untenable as a systematic approach in vertebrate model organisms given the number of surveyable genes and observable phenotypes. Unbiased prediction of gene-phenotype relationships offers a strategy to direct finite...

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Identifiers

PMID: 24346703
DOI: 10.1242/dev.099796
PMCID: PMC3865760

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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