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Article

Zebrafish nampt-a mutants are viable despite perturbed primitive hematopoiesis.

Hereditas - 29 Apr 2024

Pomreinke Autumn Penecilla, Müller Patrick

Abstract excerpt

BACKGROUND: Nicotinamide phosphoribosyltransferase (Nampt) is required for recycling NAD+ in numerous cellular contexts. Morpholino-based knockdown of zebrafish nampt-a has been shown to cause abnormal development and defective hematopoiesis concomitant with decreased NAD+ levels. However, surprisingly, nampt-a mutant zebrafish were recently found to be viable, suggesting a discrepancy between the phenotypes in...

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Identifiers

PMID: 38685093
DOI: 10.1186/s41065-024-00318-y
PMCID: PMC11057069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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