N-Acetyltransferase 2 (NAT2) gene polymorphism and exposure to smoking in lung cancer of Chinese males.

doi:10.1007/s12032-014-0090-9

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Article

N-Acetyltransferase 2 (NAT2) gene polymorphism and exposure to smoking in lung cancer of Chinese males.

Medical oncology (Northwood, London, England) - 1 Aug 2014

Tian Fangshuo, Zhang Yue, Ren Yangwu, Shen Li, Wu Wei, Zhou Baosen

Abstract excerpt

N-Acetyltransferase 2 (NAT2) is a polymorphic gene encoding the enzyme that metabolizes arylamine and hydrazine moieties. The NAT2 rs1799930 (G590A) may change drug-induced toxicity and affect cancer susceptibility. To investigate the association between NAT2 rs1799930 polymorphism and susceptibility to lung cancer, we performed a hospital-based case-control study, including 259 lung squamous carcinoma patients...

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Identifiers

PMID: 25005845
DOI: 10.1007/s12032-014-0090-9

Genes

NAT2

Variants

rs1799930

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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