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Article

[Relevance of CYP2C19 2 regarding platelet reactivity in patients with acute coronary syndrome treated with clopidogrel].

Medicina clinica - 7 Jul 2014

Cano Pedro, Consuegra-Sánchez Luciano, Conesa Pablo, Torres-Moreno Daniel, Jaulent Leticia, Dau Derek, Picó Francisco, Villegas Manuel

Abstract excerpt

BACKGROUND AND OBJECTIVE: Previous studies have shown that the metabolism of P2Y12 receptor blockers is influenced not only by CYP2C19 2 but also by PON1-Q192R alelles. We aimed to evaluate the impact of CYP2C19 2 and PON1-Q192R polymorphisms carriage in platelet reactivity and clinical outcome in patients with ischemic heart disease undergoing cardiac catheterization. PATIENTS AND METHOD: We recruited...

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Source

Identifiers

PMID: 23850044
DOI: 10.1016/j.medcli.2013.04.042

Genes

PON1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Relevance of CYP2C19 2 regarding platelet reactivity in patients with acute coronary syndrome treated with clopidogrel].PMID 23850044Read ↗

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