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Article

Spectrin βV adaptive mutations and changes in subcellular location correlate with emergence of hair cell electromotility in mammalians.

Proceedings of the National Academy of Sciences of the United States of America - 21 Feb 2017

Cortese Matteo, Papal Samantha, Pisciottano Francisco, Elgoyhen Ana Belén, Hardelin Jean-Pierre, Petit Christine, Franchini Lucia Florencia, El-Amraoui Aziz

Abstract excerpt

The remarkable hearing capacities of mammals arise from various evolutionary innovations. These include the cochlear outer hair cells and their singular feature, somatic electromotility, i.e., the ability of their cylindrical cell body to shorten and elongate upon cell depolarization and hyperpolarization, respectively. To shed light on the processes underlying the emergence of electromotility, we focused on the...

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Identifiers

PMID: 28179572
DOI: 10.1073/pnas.1618778114
PMCID: PMC5338438

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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