Article
Activity regulates a cell type-specific mitochondrial phenotype in zebrafish lateral line hair cells.
eLife - 13 Mar 2023
McQuate Andrea, Knecht Sharmon, Raible David W
Abstract excerpt
Hair cells of the inner ear are particularly sensitive to changes in mitochondria, the subcellular organelles necessary for energy production in all eukaryotic cells. There are over 30 mitochondrial deafness genes, and mitochondria are implicated in hair cell death following noise exposure, aminoglycoside antibiotic exposure, as well as in age-related hearing loss. However, little is known about the basic aspects...
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