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Article

Gene-environment interaction as a predictor of early adjustment in first episode psychosis.

Schizophrenia research - 1 Nov 2017

Fraguas David, Díaz-Caneja Covadonga M, Corripio Iluminada, González-Pinto Ana, Lobo Antonio, Bioque Miquel, Cuesta Manuel J, Sanjuán Julio, Rodríguez-Toscano Elisa, Arias Bárbara, Sarró Salvador, Cabrera Bibiana, Bulbena Antoni, Vieta Eduard, Castro-Fornieles Josefina, Arango Celso, Bernardo Miquel, Parellada Mara

Abstract excerpt

BACKGROUND: This study aims to explore the gene-environment interaction hypothesis applied to pre-symptomatic neurodevelopmental phenotypes of first episode psychosis (FEP), that is, genetic factors might increase vulnerability to the effects of environmental adverse conditions occurring at later stages of development. METHODS: We constructed a schematic 'two-hit' model, with Val/Val homozygosity for the...

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PMID: 28262436
DOI: 10.1016/j.schres.2017.02.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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