Article
Susceptibility to non-tuberculous mycobacterial disease is influenced by rs1518111 in IL10.
Human immunology - 1 Apr 2017
Halstrom Samuel, Thomson Rachel, Goullee Hayley, Baltic Svetlana, Allcock Richard, Temple Suzanna E L, Price Patricia
Abstract excerpt
Although exposure to potentially pathogenic nontuberculous mycobacteria (NTM) via soil and domestic water supplies is common, pulmonary infection and disease are confined to a small proportion of older individuals. Previously, alleles of a polymorphism in IL10 (rs1800896) were associated with NTM disease and we demonstrated elevated production of IL-10 by blood leukocytes from patients with pulmonary NTM. Here...
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