Article
Single Nucleotide Polymorphisms in IL17A and IL6 Are Associated with Decreased Risk for Pulmonary Tuberculosis in Southern Brazilian Population.
PloS one - 1 Jan 2016
Milano Mariana, Moraes Milton Ozório, Rodenbusch Rodrigo, Carvalho Caroline Xavier, Delcroix Melaine, Mousquer Gabriel, Laux da Costa Lucas, Unis Gisela, Dalla Costa Elis Regina, Rossetti Maria Lucia Rosa
Abstract excerpt
In Mycobacterium tuberculosis (MTB) infection, the complex interaction of host immune system and the mycobacteria is associated with levels of cytokines production that play a major role in determining the outcome of the disease. Several single-nucleotide polymorphisms (SNPs) in cytokine genes have been associated with tuberculosis (TB) outcome. The aim of this study was to evaluate the association between...
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