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Article

Common interleukin 10 polymorphism associated with decreased risk of tuberculosis.

Experimental & molecular medicine - 30 Apr 2005

Shin Hyoung Doo, Park Byung Lae, Kim Young Hyo, Cheong Hyun Sub, Lee In Hee, Park Seung Kyu

Abstract excerpt

Interleukin 10 (IL10) is a powerful TH2-cell cytokine that inhibits lymphocyte replication and secretion of inflammatory cytokines. The genetic associations of polymorphisms in IL10 with clinical manifestations of tuberculosis (TB) were examined in a large number of patients with clinical TB infection (n = 459) and normal controls (n = 871). One common promoter SNP (IL10 -592 A>C) was found to be significantly...

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PMID: 15886526
DOI: 10.1038/emm.2005.17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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